The Science Behind Medical Weight Loss: How It Works and Why It’s Effective

The Science Behind Medical Weight Loss

Losing weight can be daunting, and achieving significant results through diet and exercise alone is often difficult. That is where medical weight loss management comes in. Medical weight loss management involves using evidence-based medical treatments to help individuals lose weight safely and effectively. This article will explore the science behind medical weight loss management, available treatments, and their effectiveness.

Understanding the Science Behind Medical Weight Loss

Medical weight loss management is based on the understanding that obesity is a complex disease influenced by various factors, including genetics, environment, and behavior. As a result, medical weight loss management involves a multidisciplinary approach that addresses these factors through diet, exercise, medication, and behavioral therapy.

According to research, medical weight loss treatment is more effective than traditional approaches regarding weight reduction, such as food and exercise alone. A study has found that individuals who participated in a medical weight loss program lost significantly more weight than those who did not.

What are the types of medical weight loss treatments?

Several medical weight loss treatments are available at The Alchemy Clinic, including Semaglutide injections, Naltrexone SR/Bupropion SR, Metformin, and Peptides. Let us look into each one of them.

Semaglutide Injections

Semaglutide is a medication that belongs to a class of drugs called glucagon-like peptide-1 (GLP-1) receptor agonists. It mimics the effects of the natural hormone GLP-1, released by the intestines after eating. GLP-1 helps regulate blood sugar levels by stimulating insulin release, suppressing glucagon secretion, and slowing gastric emptying. Semaglutide, therefore, lowers blood sugar levels by increasing insulin secretion and reducing glucagon release. It also helps to reduce appetite and food intake, making it useful for weight management.

FDA has authorized the use of semaglutide, which is administered as a once-weekly injection to treat type 2 diabetes and obesity. In clinical trials, it effectively lowers blood sugar levels and achieves weight loss in people with diabetes and obesity.

Naltrexone SR/Bupropion SR

Naltrexone SR/Bupropion SR is a medication that promotes weight loss. It is a combination of two drugs, naltrexone and bupropion, that work together to help people lose weight. Naltrexone is typically used to treat addiction to drugs or alcohol, while bupropion is an antidepressant also used to help people quit smoking.

Combining these two drugs works in several ways to promote weight loss. Bupropion increases the levels of dopamine and norepinephrine in the brain, which can help reduce appetite and increase energy expenditure. Naltrexone, on the other hand, helps to counteract the effects of bupropion which can increase food intake. In addition to reducing the pleasant impact of food and preventing overeating, naltrexone inhibits the effects of opioids in the brain.

This medication’s naltrexone and bupropion synergistic effects on appetite suppression, increased energy expenditure, and reduced overeating are suggested to help people lose weight. In clinical trials, it is effective in achieving weight loss in people with obesity.


Metformin is frequently used to treat type 2 diabetes because it increases insulin sensitivity and decreases the amount of glucose the liver produces. It is also used off-label to promote weight loss in people with obesity. The exact mechanism of action by which metformin encourages weight loss is not fully understood, but it is believed to work by reducing appetite, increasing satiety, and improving insulin resistance.

Metformin helps to reduce appetite by increasing the levels of a hormone called glucagon-like peptide-1 (GLP-1) in the intestines, which can reduce hunger and increase feelings of fullness. It also helps reduce insulin resistance, improving metabolism and energy expenditure. Additionally, metformin has been shown to decrease the absorption of calories from food in the intestines, which can contribute to weight loss.


Peptides are a group of molecules that are made up of amino acids. They have a variety of functions in the body, including regulating appetite and metabolism. Peptides have been studied for their potential use in weight loss, and several peptides have shown promise in clinical trials.

Peptide weight loss medicine development and research are still in their development. More studies are needed to understand their potential benefits and risks fully. It is important to note that peptide medications should only be used under the guidance of a healthcare professional and in conjunction with a healthy lifestyle, including a balanced diet and regular exercise, for best results.

What are the benefits of medical weight loss management?

Medical weight loss management has several benefits over traditional weight loss methods:

  1. Medical weight loss programs are tailored to the individual, considering their unique medical history, lifestyle, and goals.
  2. Medical weight loss programs are evidence-based and effective for weight loss.
  3. Medical weight loss programs are typically supervised by a medical professional who can provide additional support and guidance.

Medical Weight Loss vs. Traditional Weight Loss Methods

While standard weight reduction techniques like diet and exercise can be successful at helping people lose weight, they are frequently difficult to maintain in the long run. Medical weight loss management, on the other hand, provides individuals with the tools and support they need to make lasting lifestyle changes.

Medical weight loss management is also more effective than traditional weight loss methods. A study published in the International Journal of Obesity found that individuals who participated in a medical weight loss program lost significantly more weight than those who participated in a traditional weight loss program.

Choosing the Right Medical Weight Loss Program

Choosing the right medical weight loss program can be a daunting task. It is essential to look for an evidence-based program supervised by a medical professional and tailored to your individual needs and goals. Before starting treatment, it is also necessary to consider any medical weight loss treatments’ potential risks and side effects.


Medical weight loss management is a safe and effective way to achieve significant weight loss. By understanding the science behind medical weight loss and the treatments available, individuals can make informed decisions about their weight loss journey. If you are interested in medical weight loss management, contact us at The Alchemy Clinic today, and we’ll guide you through the process.

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